GO Term : GO:0002432 granuloma formation GO

Namespace:  biological_process Obsolete:  false
description  The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

9 Parents

Identifier Name Description
GO:0006952 defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0006954 inflammatory response The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0002252 immune effector process Any process of the immune system that can potentially contribute to an immune response.
GO:0002432 granuloma formation The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.
GO:0002544 chronic inflammatory response Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.

17 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0002252 GO:0002432
part of GO:0002544 GO:0002432
part of GO:0006950 GO:0002432
is_a GO:0002376 GO:0002432
part of GO:0008150 GO:0002432
part of GO:0050896 GO:0002432
is_a GO:0008150 GO:0002432
part of GO:0006954 GO:0002432
part of GO:0006952 GO:0002432
regulates GO:0002432 GO:0002631
regulates GO:0002432 GO:0002631
negatively regulates GO:0002432 GO:0002632
negatively regulates GO:0002432 GO:0002632
regulates GO:0002432 GO:0002632
positively regulates GO:0002432 GO:0002633
positively regulates GO:0002432 GO:0002633
regulates GO:0002432 GO:0002633

0 Synonyms