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GO:0003677
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DNA binding
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Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
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GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
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GO:0003700
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transcription factor activity, sequence-specific DNA binding
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Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
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GO:0006355
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regulation of transcription, DNA-templated
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Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
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GO:0043565
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sequence-specific DNA binding
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Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
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GO:0006357
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regulation of transcription from RNA polymerase II promoter
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Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
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GO:0003676
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nucleic acid binding
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Interacting selectively and non-covalently with any nucleic acid. |
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GO:0007165
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signal transduction
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The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
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GO:0008289
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lipid binding
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Interacting selectively and non-covalently with a lipid. |
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GO:0004871
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signal transducer activity
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Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. |
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GO:0003690
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double-stranded DNA binding
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Interacting selectively and non-covalently with double-stranded DNA. |
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GO:0010468
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regulation of gene expression
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Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
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GO:0051252
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regulation of RNA metabolic process
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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. |
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GO:0031668
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cellular response to extracellular stimulus
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Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus. |
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GO:0004872
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receptor activity
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Combining with an extracellular or intracellular messenger to initiate a change in cell activity. |
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GO:0000981
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RNA polymerase II transcription factor activity, sequence-specific DNA binding
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Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
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GO:0051716
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cellular response to stimulus
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Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. |
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GO:0010033
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response to organic substance
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Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. |
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GO:0036094
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small molecule binding
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Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule. |
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GO:0007154
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cell communication
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Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. |
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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0004879
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RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
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Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. |
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GO:0005496
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steroid binding
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Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene. |
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GO:0044763
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single-organism cellular process
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Any process that is carried out at the cellular level, occurring within a single organism. |
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GO:0044699
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single-organism process
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A biological process that involves only one organism. |
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GO:0008150
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biological_process
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Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
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GO:0003674
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molecular_function
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Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
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GO:0050896
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response to stimulus
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Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. |
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GO:0065007
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biological regulation
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Any process that modulates a measurable attribute of any biological process, quality or function. |
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GO:0050794
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regulation of cellular process
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Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
