GO Term : GO:0039591 suppression by virus of host tapasin activity GO

Namespace:  biological_process Obsolete:  false
description  Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host tapasin (TAP binding protein/TAPBP) activity. Tapasin is a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

94 Parents

Identifier Name Description
GO:0006952 defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0031347 regulation of defense response Any process that modulates the frequency, rate or extent of a defense response.
GO:0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0016032 viral process A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.
GO:0030683 evasion or tolerance by virus of host immune response Any process, either active or passive, by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0046776 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051607 defense response to virus Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
GO:0019048 modulation by virus of host morphology or physiology The process in which a virus effects a change in the structure or processes of its host organism.
GO:0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune system process.
GO:0031348 negative regulation of defense response Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0044764 multi-organism cellular process Any process that is carried out at the cellular level which involves another organism of the same or different species.
GO:0051704 multi-organism process A biological process which involves another organism of the same or different species.
GO:0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0044092 negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0009605 response to external stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GO:0065008 regulation of biological quality Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

123 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0039507 GO:0039591
is_a GO:0046776 GO:0039591
regulates GO:0019882 GO:0039591
negatively regulates GO:0050896 GO:0039591
is_a GO:0051832 GO:0039591
is_a GO:0020012 GO:0039591
is_a GO:0044068 GO:0039591
is_a GO:0016032 GO:0039591
negatively regulates GO:0043207 GO:0039591
part of GO:0051704 GO:0039591
regulates GO:0002376 GO:0039591
is_a GO:0075528 GO:0039591
regulates GO:0002252 GO:0039591
is_a GO:0051834 GO:0039591
is_a GO:0051701 GO:0039591
is_a GO:0075136 GO:0039591
regulates GO:0051704 GO:0039591
is_a GO:0050690 GO:0039591
regulates GO:0009607 GO:0039591
regulates GO:0009605 GO:0039591
is_a GO:0009607 GO:0039591
is_a GO:0009605 GO:0039591
negatively regulates GO:0098542 GO:0039591
is_a GO:0051707 GO:0039591
negatively regulates GO:0008150 GO:0039591
regulates GO:0051707 GO:0039591
is_a GO:0051704 GO:0039591
is_a GO:0044362 GO:0039591
is_a GO:0044003 GO:0039591
negatively regulates GO:0002474 GO:0039591

3 Synonyms

Name Type
inhibition of host tapasin by virus synonym
suppression by virus of host TAP binding protein synonym
inhibition of host TAPBP by virus synonym