| Type: | Domain | Name: | Quinoprotein amine dehydrogenase, beta chain-like |
| Description: | Quinohemoprotein amine dehydrogenase (QHNDH) from Paracoccus denitrificansis a heterotrimer consisting of alpha, beta and gamma chains []. The alpha chain has a four-domain structure that includes a dihaem cytochrome c, the beta chain forms a 7-bladed beta-propeller that is part of the enzyme active site, and the gamma chain contains the redox factor cysteine tryptophylquinone (CTQ).The beta chain of QHNDH structurally resembles the 7-bladed beta propeller of the H chain of the periplasmic quinoprotein methylamine dehydrogenase (MADH), found in methylotrophic bacteria []. MADH is a heterotetramer consisting of two heavy (H) chains and two light (L) chains, and contains the redox cofactor tryptophan tryptophylquinone (TTQ). There is no similarity between the quinone-containing chains of MAD and QHNDH.The beta-propeller structure found in MAD and QHNDH is similar to the YVTN (Tyr-Val-Thr-Asn) repeat that folds into a beta-propeller found in the N-terminal domain of archaeal surface layer proteins, which help protect cells from extreme environments []. | Short Name: | Quino_amine_DH_bsu |
| DB identifier | Type | Name |
|---|---|---|
| IPR015943 | Domain | WD40/YVTN repeat-like-containing domain |
| IPR009451 | Family | Amine dehydrogenase heavy chain |
| IPR013476 | Family | Methylamine dehydrogenase heavy chain |
| IPR022456 | Family | PQQ-dependent catabolism-associated beta-propeller protein |
| IPR008311 | Family | Uncharacterised conserved protein UCP028101 |
