1 Parent Features
| DB identifier | Type | Name |
|---|---|---|
| IPR014371 | Family | Sterol O-acyltransferase, ACAT/DAG/ARE types |
| Type: | Family | Name: | Diacylglycerol O-acyltransferase 1 |
| Description: | Diacylglycerol O-acyltransferase 1 (DGAT1) catalyses the final step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In plants, diacylglycerol O-acyltransferase 1 (DGAT1, TAG1) is a major enzyme for oil accumulation in seeds. It has complementary functions with PDAT1 acyltransferase that are essential for triacylglycerol synthesis and normal development of both seeds and pollen [, , , , ].In mammals, DGAT1 is a multifunctional acyltransferase capable of synthesizing diacylglycerol, retinyl, and wax esters in addition to triacylglycerol []. In liver, it plays a role in esterifying exogenous fatty acids to glycerol []. It also functions as the major acyl-CoA retinol acyltransferase in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders []. | Short Name: | Diacylglycerol_acylTrfase1 |
| DB identifier | Type | Name |
|---|---|---|
| IPR014371 | Family | Sterol O-acyltransferase, ACAT/DAG/ARE types |
