Protein Domain : IPR004405

Type:  Family Name:  Translation release factor pelota
Description:  Pelota (known as DOM34 in yeast) binds Hbs1, which is EF1-alpha-related subfamily GTPase, and is considered to play a crucial role in mRNA surveillance for protein synthesis []. It is involved in No-go decay (NGD) and non-stop decay (NSD) surveillance mechanisms that target mRNAs on which elongation complexes are stalled. Pelota/Hbs1 were shown to promote dissociation of stalled elongation complexes and release of intact peptidyl-tRNA in the presence of the ATP-binding cassette protein ABCE1 []. Pelota is conserved in eukaryotes and archaea []. Short Name:  Transl-rel_pelota
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1 Child Features

DB identifier Type Name
IPR023521 Family Translation release factor pelota, archaea

3 Contains

DB identifier Type Name
IPR005142 Domain eRF1 domain 3
IPR005140 Domain eRF1 domain 1/Pelota-like
IPR005141 Domain eRF1 domain 2

2 Cross Referencess

Identifier
PTHR10853
TIGR00111

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0070481 IPR004405
GO:0070966 IPR004405
GO:0071025 IPR004405

3 Ontology Annotations

GO Term Gene Name
GO:0070481 IPR004405
GO:0070966 IPR004405
GO:0071025 IPR004405

0 Parent Features

759 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
81932 D8QZH2 PAC:15412096 Selaginella moellendorffii 378  
evm.TU.contig_44271.1 PAC:16431988 Carica papaya 81  
evm.model.supercontig_123.20 PAC:16407118 Carica papaya 80  
evm.model.supercontig_123.22 PAC:16407120 Carica papaya 267  
30128.m009016 B9RFU5 PAC:16818599 Ricinus communis 378  
Cucsa.277760.4 PAC:16974127 Cucumis sativus 321  
Cucsa.277760.1 A0A0A0LHC6 PAC:16974124 Cucumis sativus 379  
Cucsa.277760.2 PAC:16974125 Cucumis sativus 344  
orange1.1g042331m A0A067DYC3 PAC:18121387 Citrus sinensis 378  
orange1.1g048626m A0A067E299 PAC:18121394 Citrus sinensis 260  
orange1.1g030017m PAC:18122535 Citrus sinensis 184  
orange1.1g020502m PAC:18122530 Citrus sinensis 325  
orange1.1g020677m PAC:18122531 Citrus sinensis 323  
orange1.1g022772m PAC:18122533 Citrus sinensis 292  
orange1.1g021563m PAC:18122532 Citrus sinensis 311  
orange1.1g024840m PAC:18122534 Citrus sinensis 262  
AT4G27650.1 Q9ZT87 PAC:19644926 Arabidopsis thaliana 378  
AT3G58390.1 Q9M2H7 PAC:19659258 Arabidopsis thaliana 395  
Thhalv10025647m V4MGW4 PAC:20192890 Eutrema salsugineum 340  
Thhalv10025499m V4MNK1 PAC:20192889 Eutrema salsugineum 372  
Thhalv10025473m V4MDK4 PAC:20192888 Eutrema salsugineum 378  
Ciclev10013675m PAC:20796440 Citrus clementina 302  
Ciclev10023555m V4TUF5 PAC:20808978 Citrus clementina 378  
Lus10009553 PAC:23145741 Linum usitatissimum 378  
Lus10020376 PAC:23144038 Linum usitatissimum 380  
Potri.T158700.1 A0A2K1R4V9 PAC:27003389 Populus trichocarpa 224  
Potri.004G092600.1 A0A2K2AS50 PAC:26991952 Populus trichocarpa 363  
Potri.005G204500.1 PAC:27031909 Populus trichocarpa 375  
Potri.005G204500.2 A0A2K2AJM3 PAC:27031910 Populus trichocarpa 259  
Gorai.004G260600.4 A0A0D2RAX6 PAC:26774784 Gossypium raimondii 354  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            21448132
            18022361
            20974926