Protein Domain : IPR012132

Type:  Family Name:  Glucose-methanol-choline oxidoreductase
Description:  Proteins in this entry are members of the glucose-methanol-choline oxidoreductase family of flavoenzymes []. These enzymes catalyse diverse reaction and include glucose dehydrogenase (), alcohol oxidase (), glucose oxidase (), choline dehydrogenase (), and hydroxynitrile lyase (). Structural studies indicate that these proteins are composed of an N-terminal FAD-binding domain, and a C-terminal substrate-binding domain [, , ]. The FAD-binding domain forms the alpha-beta fold typical of dinucleotide binding proteins, while the substrate-binding domain consists of a beta sheet surrounded by alpha helices. The general topology of these proteins is conserved, though inserted structural elements occur in both choline dehydrogenase and alcohol dehydrogenase []. Short Name:  GMC_OxRdtase
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3 Child Features

DB identifier Type Name
IPR031206 Family Protein Hothead
IPR011533 Family Oxygen-dependent choline dehydrogenase
IPR023978 Family Glucose-methanol-choline oxidoreductase, actinobacteria

2 Contains

DB identifier Type Name
IPR000172 Domain Glucose-methanol-choline oxidoreductase, N-terminal
IPR007867 Domain Glucose-methanol-choline oxidoreductase, C-terminal

1 Cross References

Identifier
PIRSF000137

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0016614 IPR012132
GO:0050660 IPR012132
GO:0055114 IPR012132

3 Ontology Annotations

GO Term Gene Name
GO:0016614 IPR012132
GO:0050660 IPR012132
GO:0055114 IPR012132

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
81946 D8R0I7 PAC:15412126 Selaginella moellendorffii 525  
evm.model.supercontig_131.52 PAC:16408048 Carica papaya 571  
evm.model.supercontig_4.214 PAC:16419302 Carica papaya 567  
30147.m014326 B9R9I5 PAC:16820337 Ricinus communis 577  
28694.m000670 B9SN35 PAC:16801532 Ricinus communis 597  
Cucsa.341190.1 A0A0A0LIE5 PAC:16979189 Cucumis sativus 595  
Cucsa.360570.1 A0A0A0K7W4 PAC:16980760 Cucumis sativus 588  
orange1.1g008281m PAC:18120474 Citrus sinensis 571  
orange1.1g008675m PAC:18120475 Citrus sinensis 557  
orange1.1g012707m PAC:18120476 Citrus sinensis 458  
orange1.1g008163m PAC:18120473 Citrus sinensis 575  
orange1.1g007210m A0A067FPX9 PAC:18133091 Citrus sinensis 612  
orange1.1g011442m A0A067FP62 PAC:18133092 Citrus sinensis 485  
orange1.1g008331m A0A067EYC2 PAC:18101252 Citrus sinensis 570  
AT5G51950.1 Q94KD2 PAC:19671197 Arabidopsis thaliana 586  
AT5G51950.2 PAC:19671198 Arabidopsis thaliana 553  
AT5G51930.1 F4KEQ5 PAC:19671055 Arabidopsis thaliana 582  
AT3G56060.1 Q93ZK1 PAC:19661047 Arabidopsis thaliana 577  
AT1G12570.1 Q66GI5 PAC:19653537 Arabidopsis thaliana 572  
AT1G72970.1 Q9S746 PAC:19655560 Arabidopsis thaliana 594  
AT1G72970.2 F4IF15 PAC:19655561 Arabidopsis thaliana 567  
Thhalv10013065m V4NBN5 PAC:20203649 Eutrema salsugineum 586  
Thhalv10007216m V4L746 PAC:20186658 Eutrema salsugineum 570  
Thhalv10018308m V4KKT0 PAC:20190975 Eutrema salsugineum 600  
Ciclev10019445m V4TV60 PAC:20806364 Citrus clementina 583  
Ciclev10019427m V4TK39 PAC:20806363 Citrus clementina 587  
Ciclev10019456m V4T0T8 PAC:20806365 Citrus clementina 580  
Ciclev10025184m V4RXX5 PAC:20799758 Citrus clementina 612  
Ciclev10006541m V4SDJ3 PAC:20791739 Citrus clementina 570  
Lus10024487 PAC:23170242 Linum usitatissimum 576  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1542121
            11566130
            10194345
            10216293
            9523716