| Type: | Family | Name: | Activator of Hsp90 ATPase homologue 1-like |
| Description: | This family includes eukaryotic, prokaryotic and archaeal proteins that bear similarity to a C-terminal region of human activator of 90 kDa heat shock protein ATPase homologue 1 (AHSA1/p38, ). This protein is known to interact with the middle domain of Hsp90, and stimulate its ATPase activity []. It is probably a general up regulator of Hsp90 function, particularly contributing to its efficiency in conditions of increased stress []. p38 is also known to interact with the cytoplasmic domain of the VSV G protein, and may thus be involved in protein transport []. It has also been reported as being under expressed in Down's syndrome. This region is found repeated in two members of this family (and ). | Short Name: | Activator_of_Hsp90_ATPase |
