| Type: | Domain | Name: | Shikimate dehydrogenase substrate binding, N-terminal |
| Description: | This domain is the substrate binding domain of shikimate dehydrogenase []. Shikimate dehydrogenase catalyses the fourth step of the mycobacterial Shikimate pathway, which results in the biosynthesis of chorismate. Chorismate is a precursor of aromatic amino acids, naphthoquinones, menaquinones and mycobactins [, ]. This pathway is an important target for antibacterial agents, especially against Mycobacterium tuberculosis, since it does not occur in mammals. | Short Name: | Shikimate_DH-bd_N |
