Type: | Domain | Name: | Transcription Factor IIF, Rap30/Rap74, interaction |
Description: | Transcription factor IIF (TFIIF), which is essential for eukaryotic transcription by RNA polymerase II. (PolII), consists of a heterodimer of Rap30 (beta) () and Rap74 (alpha) () subunits []. Rap30 and Rap74 have multiple domains that bind to PolII, TFIIB, TAF250 and DNA in interactions that are essential for transcription initiation and elongation. The N-terminal interactions domains of Rap30 and Rap74 are responsible for establishing the dimer interface between the two subunits, this interface being important for TFIIF function []. | Short Name: | TFIIF_interaction |