Protein Domain : IPR016636

Type:  Family Name:  3-oxo-5-alpha-steroid 4-dehydrogenase
Description:  Synonym(s): Steroid 5-alpha-reductase3-oxo-5-alpha-steroid 4-dehydrogenases, catalyse the conversion of 3-oxo-5-alpha-steroid + acceptor to 3-oxo-delta(4)-steroid + reduced acceptor. The steroid 5-alpha-reductase enzyme is responsible for the formation of dihydrotestosterone, this hormone promotes the differentiation of male external genitalia and the prostate during foetal development []. In humans mutations in this enzyme can cause a form of male pseudohermaphorditism in which the external genitalia and prostate fail to develop normally. Short Name:  3-oxo-5-alpha-steroid_4-DH
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0 Child Features

1 Contains

DB identifier Type Name
IPR001104 Domain 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal

1 Cross References

Identifier
PIRSF015596

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0003865 IPR016636
GO:0008202 IPR016636
GO:0055114 IPR016636
GO:0016020 IPR016636

4 Ontology Annotations

GO Term Gene Name
GO:0003865 IPR016636
GO:0008202 IPR016636
GO:0055114 IPR016636
GO:0016020 IPR016636

0 Parent Features

195 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
233670 D8SCW6 PAC:15401883 Selaginella moellendorffii 220  
Potri.T122200.1 PAC:27014209 Populus trichocarpa 264  
Potri.016G110600.1 B9IG44 PAC:27012072 Populus trichocarpa 257  
Potri.005G047800.1 PAC:27030631 Populus trichocarpa 264  
SapurV1A.0048s0810.1.p PAC:31454247 Salix purpurea 265  
SapurV1A.2551s0020.1.p PAC:31423225 Salix purpurea 265  
SapurV1A.1036s0050.1.p PAC:31439354 Salix purpurea 244  
AUR62011054-RA PAC:36312508 Chenopodium quinoa 259  
AUR62033432-RA PAC:36284222 Chenopodium quinoa 260  
Phvul.008G108600.1.p V7B7E4 PAC:37158880 Phaseolus vulgaris 261  
Potri.005G047800.1.p PAC:37265969 Populus trichocarpa 264  
Potri.T122200.1.p PAC:37251048 Populus trichocarpa 264  
Potri.016G110600.1.p B9IG44 PAC:37249425 Populus trichocarpa 257  
Podel.05G050300.1.p PAC:37316378 Populus deltoides WV94 254  
Podel.13G144900.1.p PAC:37334380 Populus deltoides WV94 298  
Podel.16G116700.1.p PAC:37300289 Populus deltoides WV94 257  
Bol025274 A0A3P6CIR2 PAC:37340365 Brassica oleracea capitata 261  
AT2G38050.1 Q38944 PAC:37379406 Arabidopsis thaliana 262  
PGSC0003DMP400035350 PAC:37458615 Solanum tuberosum 259  
PGSC0003DMP400033356 PAC:37477890 Solanum tuberosum 239  
Anaoc.0001s0100.1.p PAC:37548797 Anacardium occidentale 258  
Pavir.5KG534300.1.p PAC:37639147 Panicum virgatum 263  
Pavir.5KG534300.3.p PAC:37639149 Panicum virgatum 263  
Pavir.5KG534300.2.p PAC:37639148 Panicum virgatum 263  
Pavir.8NG284200.1.p PAC:37625504 Panicum virgatum 268  
Oeu040800.1 PAC:37703857 Olea europaea 269  
evm.model.Scaffold_571.192 PAC:37886784 Coffea arabica 273  
Sobic.003G358400.2.p C5XPU8 PAC:37918443 Sorghum bicolor 264  
Sobic.003G358400.3.p C5XPU8 PAC:37918444 Sorghum bicolor 264  
VIT_208s0007g01760.1 A0A438BY97 PAC:38022986 Vitis vinifera 257  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1686016