Protein Domain : IPR019412

Type:  Family Name:  Outer membrane protein Iml2/Tetratricopeptide repeat protein 39
Description:  This entry represents a family of proteins conserved from fungi to humans, including fungal Iml2 protein, animal tetratricopeptide repeat protein 39A/B/C (TT39A/B/C) and some characterised proteins. Members of this family carry a tetratricopeptide repeat () at their C terminus. In Saccharomyces cerevisiae, Iml2 and its paralogue-YKR018C are included in this entry. Iml2 localises to the cytoplasm and nucleus [], and its expression is increased in response to DNA replication stress []. In humans TTC39A (also known as DEME6) is expressed in primary breast carcinomas but not in normal breast tissue, and has a putative eukaryotic RNP-1 RNA binding region and a candidate anchoring transmembrane domain. It is coordinately regulated with oestrogen receptor, but is not necessarily oestradiol-responsive []. TTC39B has been linked to lipid metabolism [, ]. Short Name:  OMP_Iml2/TPR_39
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1 Child Features

DB identifier Type Name
IPR030416 Family Tetratricopeptide repeat protein 39

0 Contains

1 Cross References

Identifier
PF10300

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

28 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
420540 D8SCB8 PAC:15413715 Selaginella moellendorffii 590  
123922 D8SSG2 PAC:15404802 Selaginella moellendorffii 668  
193644 PAC:27341314 Micromonas pusilla CCMP1545 766  
Sphfalx0178s0017.1.p PAC:32600964 Sphagnum fallax 661  
Sphfalx0178s0017.2.p PAC:32600965 Sphagnum fallax 532  
Pp3c17_3870V3.2.p PAC:32907962 Physcomitrium patens 572  
Pp3c17_3870V3.1.p A0A2K1J2M3 PAC:32907961 Physcomitrium patens 696  
Pp3c25_5600V3.1.p A0A2K1IDW8 PAC:32979460 Physcomitrium patens 634  
Pp3c25_5600V3.3.p A0A2K1IDW8 PAC:32979462 Physcomitrium patens 634  
Pp3c25_5600V3.2.p A0A2K1IDW8 PAC:32979461 Physcomitrium patens 634  
Pp3c25_5600V3.4.p PAC:32979459 Physcomitrium patens 635  
Mapoly0016s0143.2.p A0A2R6XG64 PAC:33026966 Marchantia polymorpha 523  
Mapoly0016s0143.1.p A0A2R6XG72 PAC:33026965 Marchantia polymorpha 708  
Mapoly0033s0044.1.p A0A2R6X6A5 PAC:33003755 Marchantia polymorpha 843  
Sphmag08G060400.2.p PAC:41926888 Sphagnum magellanicum 535  
Sphmag08G060400.1.p PAC:41926887 Sphagnum magellanicum 664  
Sphfalx08G064800.2.p PAC:41992788 Sphagnum fallax 532  
Sphfalx08G064800.1.p PAC:41992787 Sphagnum fallax 661  
CepurR40.5G151600.1.p PAC:43019624 Ceratodon purpureus R40 656  
CepurR40.10G149300.1.p PAC:42999487 Ceratodon purpureus R40 551  
CepurGG1.5G144500.1.p PAC:43041110 Ceratodon purpureus GG1 703  
CepurGG1.10G143400.1.p PAC:43060438 Ceratodon purpureus GG1 511  
Ceric.06G066500.4.p PAC:50619760 Ceratopteris richardii 651  
Ceric.06G066500.3.p PAC:50619761 Ceratopteris richardii 651  
Ceric.06G066500.1.p PAC:50619758 Ceratopteris richardii 747  
Ceric.06G066500.2.p PAC:50619759 Ceratopteris richardii 706  
Ceric.21G073200.2.p PAC:50604040 Ceratopteris richardii 658  
Ceric.21G073200.1.p PAC:50604039 Ceratopteris richardii 659  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            14562095
            22842922
            9461476
            20686565
            21738485