1 Found In
| DB identifier | Type | Name |
|---|---|---|
| IPR017148 | Family | Vacuolar protein sorting-associated protein 13, fungi |
| Type: | Domain | Name: | Vacuolar protein sorting-associated protein 13, SHR-binding domain |
| Description: | This entry represents a domain, known as SHR-BD, found in vacuolar protein sorting-associated protein 13 (VPS13). In plants, this domain is found to be the region which interacts with SHR or the SHORT-ROOT transcription factor, a regulator of root-growth and asymmetric cell division that separates ground tissue into endodermis and cortex. The plant protein containing the SHR-BD is named SHRUBBY or SHBY () [].Proteins containing this domain may play a role in the control of protein cycling through the trans-Golgi network. Vacuolar sorting protein is an ATPase required for endosomal trafficking []. Defects in the human protein VPS13A cause chorea-acanthocytosis, an autosomal recessive neurodegenerative disorder characterised by the gradual onset of hyperkinetic movements and abnormal erythrocyte morphology []. | Short Name: | SHR-BD |
| DB identifier | Type | Name |
|---|---|---|
| IPR017148 | Family | Vacuolar protein sorting-associated protein 13, fungi |
