| Type: | Domain | Name: | Aerobic respiration control sensor protein ArcB, transmembrane domain |
| Description: | Histidine kinase receptors (HKR) are part of a two-component system, in which an HKR in the bacterial inner membrane transmits a signal to a response regulator located in the cytoplasm.Escherichia coli sensor kinase ArcB phosphorylates the partner response regulator ArcA in response to anaerobic conditions []. ArcB is an atypical sensor kinase containing multiple phosphorylation domains: a histidine-containing phosphotransfer (HPt) signaling domain and a receiver domain in addition to the receptor and histidine-kinase (transmitter) domains, which are the two domains constituting a typical sensor kinase [, ].ArcB is a class 2 histidine kinase receptor (HKR). Class 2 HKRs lack an apparent extracytoplasmic domain and the stimuli-sensing region is believed to be in the membrane domain itself. ArcB has two transmembrane (TM) helices connected by a short periplasmic loop. This entry represents this transmembrane domain consisting of two helical motifs []. | Short Name: | ArcB_TM |
