1 Contains
| DB identifier | Type | Name |
|---|---|---|
| IPR015421 | Domain | Pyridoxal phosphate-dependent transferase, major region, subdomain 1 |
3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0030170 | IPR010970 |
| GO:0031071 | IPR010970 |
| GO:0006534 | IPR010970 |
| Type: | Family | Name: | Cysteine desulfurase, SufS |
| Description: | Cysteine desulfurases are pyridoxal-phosphate enzymes which catalyse the removal of sulphur from L-cysteine to form L-alanine and elemental sulphur. These enzymes have been shown to play an important role in the biosynthesis of iron-sulphur clusters, thionucleosides in tRNA, thiamine, biotin, lipoate and molydopterin [].This entry represents a subfamily of NifS-related cysteine desulfurases that are often involved in iron-sulphur cluster formation, which is needed for nitrogen fixation and other vital functions []. Many of these enzymes, in addition to cysteine desulfurase activity, also show selenocysteine lyase activity where L-selenocysteine is converted to L-alanine and selenide []. Some of these enzymes are much more specific for selenocysteine than cysteine and are thus believed to function in selenium metabolism rather than sulphur metabolism.Structural studies of the Escherichia coli[] and Synechocystis [] enzymes indicate that they are homodimers which show a similar fold to other members of the alpha family of pyridoxal-phosphate enzymes []. | Short Name: | Cys_dSase_SufS |
| DB identifier | Type | Name |
|---|---|---|
| IPR015421 | Domain | Pyridoxal phosphate-dependent transferase, major region, subdomain 1 |
| GO Term | Gene Name |
|---|---|
| GO:0030170 | IPR010970 |
| GO:0031071 | IPR010970 |
| GO:0006534 | IPR010970 |
