1 Parent Features
DB identifier | Type | Name |
---|---|---|
IPR027417 | Domain | P-loop containing nucleoside triphosphate hydrolase |
Type: | Domain | Name: | Chromosomal replication initiator protein DnaA |
Description: | This entry represents the central domain of bacterial DnaA proteins [, , ] which play an important role in initiating and regulating chromosomal replication. DnaA is an ATP- and DNA-binding protein. It binds specifically to 9 bp nucleotide repeats known as dnaA boxes which are found in the chromosome origin of replication (oriC).DnaA is a protein of about 50 kDa that contains two conserved regions: the first is located in the N-terminal half and corresponds to the ATP-binding domain, the second is located in the C-terminal half and could be involved in DNA-binding. The protein may also bind the RNA polymerase beta subunit, the dnaB and dnaZ proteins, and the groE gene products (chaperonins) []. | Short Name: | DnaA |
DB identifier | Type | Name |
---|---|---|
IPR027417 | Domain | P-loop containing nucleoside triphosphate hydrolase |