Type: | Family | Name: | Histidinol-phosphate aminotransferase family |
Description: | The histidinol phosphate aminotransferase family consists of class I pyridoxal-5'-phosphate (PLP)-dependent enzymes that catalyze a step of L-histidine biosynthesis []. These proteins are highly specific enzymes inthe sense that no other aminotransferases are known to be capable of utilizing imidazoleacetol phosphate, with deletions leading to auxotrophy. A subgroup of these enzymes have broader substrate specificity and are capable of using aromatic amino acid substrates in vitro and in vivo | Short Name: | HisP_aminotrans |