| Type: | Domain | Name: | SAICAR synthetase/ADE2, N-terminal |
| Description: | Phosphoribosylaminoimidazole-succinocarboxamide synthase () (SAICAR synthetase) catalyses the seventh step in the de novopurine biosynthetic pathway; the ATP-dependent conversion of 5'-phosphoribosyl-5-aminoimidazole-4-carboxylic acid and aspartic acid to SAICAR [].This domain can be found in SAICAR synthetases as a monofunctional protein from the bacteria (purC), fungi (ADE1) and plants (Pur7). In animals, this domain can be found in the N-terminal domain of a multifunctional enzyme (ADE2) possessing both the SAICAR synthetase and the phosphoribosylaminoimidazole carboxylase (AIR carboxylase) activity. | Short Name: | SAICAR_synt/ADE2_N |
