Type: | Family | Name: | Peptidase C45 |
Description: | The peptidase C45 family includes acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferases from fungi. The active site residue for members of this family and family T1 is C-terminal to the autolytic cleavage site. In Penicillium chrysogenum, A:6-aminopenicillanic-acid-acyltransferase serves as the last enzyme in penicillin biosynthetic pathway, which converts isopenicillin N (IPN) to penicillin G, using phenyl-acetyl-CoA or phenoxyacetyl-CoA as acyl donors []. This entry also includes a number of uncharacterised proteins from bacteria, archaea, animals and plants. | Short Name: | Peptidase_C45 |