Protein Domain : IPR000831

Type:  Family Name:  Trp repressor
Description:  The Trp repressor (TrpR) binds to at least five operators in the Escherichia coligenome, repressing gene expression. The operators at which it binds vary considerably in DNA sequence and location within the promoter; when bound to the Trp operon it recognises the sequence 5'-ACTAGT-3' and acts to prevent the initiation of transcription. The TrpR controls the trpEDCBA (trpO) operon and the genes for trpR, aroH, mtr and aroL, which are involved in the biosynthesis and uptake of the amino acid tryptophan []. The repressor binds to the operators only in the presence of L-tryptophan, thereby controlling the intracellular level of its effector; the complex also regulates Trp repressor biosynthesis by binding to its own regulatory region. TrpR acts as a dimer that is composed of identical 6-helical subunits, where four of the helices form the core of the protein and intertwine with the corresponding helices from the other subunit. Short Name:  Trp_repress
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2 Child Features

DB identifier Type Name
IPR013368 Family TrpR homologue YerC/YecD
IPR013335 Family Trp repressor, bacterial

0 Contains

2 Cross Referencess

Identifier
PF01371
G3DSA:1.10.1270.10

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003700 IPR000831
GO:0006355 IPR000831
GO:0005622 IPR000831

3 Ontology Annotations

GO Term Gene Name
GO:0003700 IPR000831
GO:0006355 IPR000831
GO:0005622 IPR000831

0 Parent Features

255 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
orange1.1g027192m A0A067H6D2 PAC:18102658 Citrus sinensis 226  
orange1.1g027219m A0A067H6D2 PAC:18102659 Citrus sinensis 226  
orange1.1g028154m A0A067GU51 PAC:18102660 Citrus sinensis 213  
Ciclev10032728m V4TKJ5 PAC:20803794 Citrus clementina 215  
Ciclev10032725m V4TKJ5 PAC:20803793 Citrus clementina 215  
Potri.009G001200.1 A0A2K1Z0E4 PAC:26986561 Populus trichocarpa 95  
Gorai.005G031200.1 A0A0D2REU5 PAC:26803097 Gossypium raimondii 459  
Gorai.009G222100.1 A0A0D2S641 PAC:26762229 Gossypium raimondii 478  
51378 PAC:27340540 Micromonas pusilla CCMP1545 365  
Migut.G00712.1.p A0A022QRX1 PAC:28942442 Mimulus guttatus 475  
Migut.N00401.1.p A0A022QVE7 PAC:28923854 Mimulus guttatus 463  
Glyma.11G255600.1.p I1LN20 PAC:30531638 Glycine max 438  
Glyma.14G118600.1.p K7M762 PAC:30533183 Glycine max 67  
Glyma.17G246700.1.p K7MNT1 PAC:30479081 Glycine max 94  
Medtr3g111190.2 G7J443 PAC:31060646 Medicago truncatula 435  
Medtr3g111190.1 G7J442 PAC:31060645 Medicago truncatula 531  
Traes_1BS_ECC64577E.2 PAC:32003107 Triticum aestivum 240  
Traes_1BS_ECC64577E.4 PAC:32003109 Triticum aestivum 231  
Traes_1BS_ECC64577E.3 PAC:32003108 Triticum aestivum 231  
Traes_1DS_C146F1E11.10 PAC:31768635 Triticum aestivum 413  
Traes_1DS_C146F1E11.11 PAC:31768634 Triticum aestivum 413  
Traes_1DS_C146F1E11.9 PAC:31768636 Triticum aestivum 413  
Traes_1DS_C146F1E11.8 PAC:31768633 Triticum aestivum 413  
Traes_3AS_FD533FE2B.1 PAC:32022417 Triticum aestivum 226  
Eucgr.H00044.1.p A0A059ATE3 PAC:32042278 Eucalyptus grandis 457  
Eucgr.L00647.1.p A0A058ZX47 PAC:32042433 Eucalyptus grandis 132  
Prupe.4G230800.1.p A0A251PPT8 PAC:32094463 Prunus persica 158  
Kalax.0142s0066.1.p PAC:32591062 Kalanchoe laxiflora 213  
Pp3s32_260V3.1.p PAC:32948413 Physcomitrium patens 2208  
LOC_Os06g06570.1 PAC:33147443 Oryza sativa 132  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12475235