Protein Domain : IPR001869

Type:  Family Name:  Thiol-activated cytolysin
Description:  Thiol-activated cytolysins [] are toxins produced by a variety of Gram-positive bacteria and are characterised by their ability to lyse cholesterol-containing membranes, their reversible inactivation by oxidation and their capacity to bind to cholesterol. All these proteins contain a single cysteine residue, located in their C-terminal section, which has been shown [] to be essential for the binding to cholesterol. Short Name:  Thiol_cytolysin
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0 Child Features

0 Contains

5 Cross Referencess

Identifier
PF01289
PR01400
PS00481
G3DSA:3.90.840.10
SSF56978

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0015485 IPR001869
GO:0009405 IPR001869

2 Ontology Annotations

GO Term Gene Name
GO:0015485 IPR001869
GO:0009405 IPR001869

0 Parent Features

87 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
orange1.1g015839m A0A067FMP9 PAC:18117331 Citrus sinensis 399  
orange1.1g015203m A0A067FE97 PAC:18117330 Citrus sinensis 411  
orange1.1g008136m A0A067EV53 PAC:18116222 Citrus sinensis 576  
AT2G41780.2 O22942 PAC:19642001 Arabidopsis thaliana 127  
AT2G41780.1 O22942 PAC:19642000 Arabidopsis thaliana 127  
Ciclev10019227m V4TY45 PAC:20812023 Citrus clementina 652  
Ciclev10019475m V4VTX6 PAC:20812025 Citrus clementina 576  
Ciclev10019542m V4TT59 PAC:20812027 Citrus clementina 557  
Gorai.012G128700.1 A0A0D2V4R6 PAC:26827385 Gossypium raimondii 1274  
Cagra.0578s0017.1.p PAC:28898770 Capsella grandiflora 257  
SapurV1A.6212s0010.1.p PAC:31433104 Salix purpurea 787  
Traes_1AL_9232CDB5C.2 PAC:31921592 Triticum aestivum 420  
Traes_1AL_9232CDB5C.3 PAC:31921593 Triticum aestivum 389  
Traes_1AL_9232CDB5C.4 PAC:31921595 Triticum aestivum 205  
Traes_1AL_9232CDB5C.1 PAC:31921594 Triticum aestivum 348  
Traes_1BL_B2EEA7CF7.3 PAC:31754281 Triticum aestivum 175  
Kalax.0082s0044.1.p PAC:32548941 Kalanchoe laxiflora 477  
Pp3c2_21380V3.1.p PAC:32935330 Physcomitrium patens 194  
Pp3c2_21380V3.2.p PAC:32935331 Physcomitrium patens 194  
DCAR_021474 PAC:36083997 Daucus carota 52  
AT2G41780.1 O22942 PAC:37381275 Arabidopsis thaliana 127  
AT2G41780.2 O22942 PAC:37381276 Arabidopsis thaliana 127  
Oeu008883.1 PAC:37706281 Olea europaea 203  
Oeu051047.1 PAC:37712460 Olea europaea 400  
Oeu050504.1 PAC:37712168 Olea europaea 448  
Sobic.007G119200.2.p A0A1Z5R9D4 PAC:37934129 Sorghum bicolor 646  
Sobic.007G119200.1.p C5YKM8 PAC:37934128 Sorghum bicolor 741  
VIT_211s0149g00074.1 PAC:38065113 Vitis vinifera 223  
Gohir.D04G143100.1.p PAC:38075657 Gossypium hirsutum 1445  
SbRio.07G128200.2.p PAC:38974537 Sorghum bicolor Rio 622  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2888650
            2254290