Protein Domain : IPR018191

Type:  Family Name:  4-oxalocrotonate tautomerase, Pseudomonas-type
Description:  4-Oxalocrotonate tautomerase,is an enzyme that converts 2-hydroxymuconate to the alpha-beta-unsaturated ketone, 2-oxo-3-hexenedioate []. This enzyme forms part of a bacterial metabolic pathway that oxidatively catabolizes toluene, o-xylene, 3-ethyltoluene, and 1,2,4-trimethylbenzene into intermediates of the citric acid cycle. With a monomer size of just 62 amino acid residues, the 4-Oxalocrotonate tautomerase is one of the smallest enzyme subunits known []. However, in solution, the enzyme forms a hexamer of six identical subunits, so the active site may be formed by amino acid residues from several subunits []. This enzyme is also unusual in that it uses a proline residue at the amino terminus as an active site residue.This entry represents a group of 4-oxalocrotonate tautomerases found in Pseudomonas [] and other species of bacteria and archaea. Short Name:  Tautomerase_Pseudo-typ
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0 Child Features

1 Contains

DB identifier Type Name
IPR014347 Domain Tautomerase/MIF superfamily

1 Cross References

Identifier
TIGR00013

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0016853 IPR018191
GO:0006725 IPR018191

2 Ontology Annotations

GO Term Gene Name
GO:0016853 IPR018191
GO:0006725 IPR018191

0 Parent Features

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Pp3s30_570V3.1.p PAC:32948498 Physcomitrium patens 67  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12051677
            8547259
            1339435