Protein Domain : IPR004175

Type:  Family Name:  RNA 2',3'-cyclic phosphodiesterase
Description:  Members of this entry are bacterial and archaeal RNA cyclic phosphodiesterases (CPDases). They hydrolyse RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester []. In vitro, they are able to ligate half-tRNA molecules [], though the RNA ligase activity appears to be weak in archaea []. Each member of this family contains an internal duplication, each of which contains an HXTX motif that defines the family. They belong to the 2H phosphoeseterase superfamily [, ]. They share a common active site, characterised by two conserved histidines, with vertebrate myelin-associated 2',3' phosphodiesterases, plant Arabidopsis thaliana(Mouse-ear cress) CPDases and several several bacteria and virus proteins []. Short Name:  RNA_CPDase
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0 Child Features

2 Contains

DB identifier Type Name
IPR009097 Domain RNA ligase/cyclic nucleotide phosphodiesterase
IPR014051 Domain Phosphoesterase, HXTX

2 Cross Referencess

Identifier
TIGR02258
MF_01940

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0004113 IPR004175
GO:0008664 IPR004175

2 Ontology Annotations

GO Term Gene Name
GO:0004113 IPR004175
GO:0008664 IPR004175

0 Parent Features

1 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Pp3s70_190V3.1.p PAC:32963368 Physcomitrium patens 588  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11080166
            12466548
            8940112
            12798681
            19155324
            25239919