| Type: | Domain | Name: | Agglutinin domain |
| Description: | Agglutinins are sugar-specific lectins that can agglutinate erythrocytes and other cell types. Lectins occur widely in plants, as well as some microorganisms and animal []. Agglutinin from Amaranthus caudatus(amaranthin) is a lectin from the ancient South American crop, amaranth grain. Although its biological function is unknown, it can agglutinate A, B and O red blood cells, and has a carbohydrate-binding site that is specific for the methyl-glycoside of the T-antigen found linked to serine or threonine residues of cell surface glycoproteins []. The protein is comprised of a homodimer, with each homodimer consisting of two beta-trefoil domains []. Lectin B chains from ricin and related toxins also contain beta-trefoil domain, however they are not related to agglutinin, showing little sequence similarity []. | Short Name: | Agglutinin |
