Type: | Domain | Name: | TIM-barrel domain, IGPS-like |
Description: | This domain is likely to have a TIM barrel fold, related to IGPS (indole-3-glycerol-phosphate synthase). Interestingly, this novel domain also exists as an N-terminal domain of a putative sigma54-dependent transcriptional activator. Because sigma54dependent activators typically have a three-domain structure: the variable N-terminal regulatory (activation) domain involved in signal recognition/receiving, the central AAA-type ATPase domain, and the DNA-binding domain (see , , , for details), the domain described by this entry may be predicted to play a role in signal recognition/receiving and signal transduction. However this has not been experimentally validated. | Short Name: | TIM-br_IGPS-like |