Protein Domain : IPR028290

Type:  Family Name:  WASH1
Description:  This entry represents members of the WASH1 family, which are components of the WASH complex that is present at the surface of endosomes and activates the Arp2/3-mediated F-actin polymerisation []. WASH1 contains N-terminal WASH homology regions (also known as the WAHD domain, which covers the WHD1/EVH1 and WHD2 domains), a proline-rich region and a C-terminal WH2 domain []. WASH1 localises to early endosomal subdomains through an essential interaction with FAM21 via its WHD1 domain and directly binds tubulin through its WHD2 domain, while linking to Arp2/3-mediated F-actin polymerisation via its C-terminal WH2 domain []. Short Name:  WASH1
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR23331

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0043014 IPR028290
GO:0034314 IPR028290
GO:0005769 IPR028290
GO:0071203 IPR028290

4 Ontology Annotations

GO Term Gene Name
GO:0043014 IPR028290
GO:0034314 IPR028290
GO:0005769 IPR028290
GO:0071203 IPR028290

0 Parent Features

42 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
402573 D8QR40 PAC:15405094 Selaginella moellendorffii 449  
33632 A4S306 PAC:27413926 Ostreococcus lucimarinus 497  
Sphfalx0031s0114.2.p PAC:32613479 Sphagnum fallax 580  
Sphfalx0031s0114.1.p PAC:32613478 Sphagnum fallax 591  
Pp3c18_12360V3.8.p PAC:32981192 Physcomitrium patens 578  
Pp3c18_12360V3.17.p PAC:32981190 Physcomitrium patens 596  
Pp3c18_12360V3.7.p PAC:32981191 Physcomitrium patens 578  
Pp3c18_12360V3.16.p PAC:32981189 Physcomitrium patens 602  
Pp3c18_12360V3.9.p PAC:32981182 Physcomitrium patens 607  
Pp3c18_12360V3.6.p A0A2K1J0T0 PAC:32981199 Physcomitrium patens 570  
Pp3c18_12360V3.3.p A0A2K1J0T0 PAC:32981196 Physcomitrium patens 570  
Pp3c18_12360V3.4.p A0A2K1J0T0 PAC:32981197 Physcomitrium patens 570  
Pp3c18_12360V3.2.p A0A2K1J0T0 PAC:32981195 Physcomitrium patens 570  
Pp3c18_12360V3.15.p PAC:32981193 Physcomitrium patens 573  
Pp3c18_12360V3.1.p A0A2K1J0T0 PAC:32981194 Physcomitrium patens 570  
Pp3c18_12360V3.11.p PAC:32981184 Physcomitrium patens 607  
Pp3c18_12360V3.14.p PAC:32981187 Physcomitrium patens 607  
Pp3c18_12360V3.18.p PAC:32981188 Physcomitrium patens 607  
Pp3c18_12360V3.5.p A0A2K1J0T0 PAC:32981198 Physcomitrium patens 570  
Pp3c18_12360V3.10.p PAC:32981183 Physcomitrium patens 607  
Pp3c18_12360V3.12.p PAC:32981185 Physcomitrium patens 607  
Pp3c18_12360V3.13.p PAC:32981186 Physcomitrium patens 607  
Mapoly0129s0033.1.p A0A2R6W8F8 PAC:33005999 Marchantia polymorpha 571  
Misin01G105400.1.p PAC:40459191 Miscanthus sinensis 214  
Sphmag13G054300.8.p PAC:41917178 Sphagnum magellanicum 525  
Sphmag13G054300.7.p PAC:41917177 Sphagnum magellanicum 525  
Sphmag13G054300.3.p PAC:41917176 Sphagnum magellanicum 555  
Sphmag13G054300.5.p PAC:41917175 Sphagnum magellanicum 583  
Sphmag13G054300.1.p PAC:41917171 Sphagnum magellanicum 645  
Sphmag13G054300.4.p PAC:41917174 Sphagnum magellanicum 583  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            19922875
            19922874