1 Child Features
| DB identifier | Type | Name |
|---|---|---|
| IPR026562 | Family | Probable transcriptional regulatory protein YeeN |
| Type: | Family | Name: | Transcriptional regulator TACO1-like |
| Description: | This is a family of transcriptional regulators. In mammals, TACO1 () activates the transcription of mitochondrially-encoded cytochrome c oxidase (COX1). Defects in TACO1 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterised by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency []. In Pseudomonas aeruginosa, a member of this family, PmpR, is involved in regulation of the quinolone signal (PQS) system and of pyocyanine production. It negatively regulates the quorum-sensing response regulator pqsR of the PQS system by binding to its promoter region []. | Short Name: | Transcrip_reg_TACO1-like |
| DB identifier | Type | Name |
|---|---|---|
| IPR026562 | Family | Probable transcriptional regulatory protein YeeN |
