Type: | Family | Name: | Prefoldin |
Description: | The Prefoldin/GimC family of proteins are found in eukaryotes and archaea []. Prefoldin is part of a molecular chaperone system that promotes the correct folding of nascent polypeptide chains. Prefoldin/GimC interacts with the nascent chain to stabilise it prior to its folding within the central cavity of a chaperonin. Prefoldin/GimC is a hexamer consisting of two types of subunits, alpha and beta. Archaeal prefoldin contains one type of alpha and one type of beta subunit [], while eukaryotic prefoldin/GimC contains two different but related alpha subunits and four related beta subunits []. | Short Name: | Prefoldin |