Protein Domain : IPR017770

Type:  Family Name:  RNA 3'-terminal phosphate cyclase type 1
Description:  RNA cyclases are a family of RNA-modifying enzymes that are conserved in eukaryotes, bacteria and archaea. Type 1 RNA 3'-terminal phosphate cyclases () [, ] catalyse the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA:ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate The physiological function of the cyclase is not known, but the enzyme could be involved in the maintenance of cyclic ends in tRNA splicing intermediates or in the cyclisation of the 3' end of U6 snRNA [].A second subfamily of RNA 3'-terminal phosphate cyclases (type 2) that do not have cyclase activity have been identified in eukaryotes. They are localised to the nucleolus and are involved in ribosomal modification [].This entry represents the type 1 RNA 3'-terminal phosphate cyclases. Short Name:  RNA3'_term_phos_cyc_type_1
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0 Child Features

3 Contains

DB identifier Type Name
IPR013792 Domain RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta
IPR013791 Domain RNA 3'-terminal phosphate cyclase, insert domain
IPR020719 Conserved_site RNA 3'-terminal phosphate cyclase-like, conserved site

2 Cross Referencess

Identifier
TIGR03399
MF_00200

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0003963 IPR017770
GO:0006396 IPR017770

2 Ontology Annotations

GO Term Gene Name
GO:0003963 IPR017770
GO:0006396 IPR017770

1 Parent Features

DB identifier Type Name
IPR000228 Family RNA 3'-terminal phosphate cyclase

8 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
3085 D8QRF1 PAC:15409929 Selaginella moellendorffii 337  
33699 I0YT26 PAC:27391811 Coccomyxa subellipsoidea C-169 412  
Cre01.g053288.t1.2 A0A2K3E872 PAC:30788336 Chlamydomonas reinhardtii 453  
Cre01.g053288.t2.1 A0A2K3E873 PAC:30788337 Chlamydomonas reinhardtii 441  
Mapoly0071s0005.1.p A0A2R6WNG0 PAC:33007931 Marchantia polymorpha 387  
Cz09g02230.t1 PAC:38238757 Chromochloris zofingiensis 410  
Bobra.101_2s0030.1.p PAC:40720981 Botryococcus braunii 376  
Ceric.38G015400.1.p PAC:50579962 Ceratopteris richardii 353  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9184239
            2199762
            10790377