Protein Domain : IPR008049

Type:  Family Name:  DNA replication licensing factor Mcm6
Description:  In eukaryotes, Mcm6 is a component of the MCM2-7 complex (MCM complex), which consists of six sequence-related AAA + type ATPases/helicases that form a hetero-hexameric ring []. MCM2-7 complex is part of the pre-replication complex (pre-RC). In G1 phase, inactive MCM2-7 complex is loaded onto origins of DNA replication [, , ]. During G1-S phase, MCM2-7 complex is activated to unwind the double stranded DNA and plays an important role in DNA replication forks elongation [].The components of the MCM2-7 complex are: . DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, DNA replication licensing factor MCM5, DNA replication licensing factor MCM6, DNA replication licensing factor MCM7, Short Name:  MCM6

0 Child Features

1 Contains

DB identifier Type Name
IPR012340 Domain Nucleic acid-binding, OB-fold

2 Cross Referencess

Identifier
PTHR11630:SF43
PR01662

0 Found In

6 GO Annotations

GO Term Gene Name
GO:0003677 IPR008049
GO:0003678 IPR008049
GO:0005524 IPR008049
GO:0006270 IPR008049
GO:0005634 IPR008049
GO:0042555 IPR008049

6 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR008049
GO:0003678 IPR008049
GO:0005524 IPR008049
GO:0006270 IPR008049
GO:0005634 IPR008049
GO:0042555 IPR008049

0 Parent Features

572 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
438068 D8QT69 PAC:15418129 Selaginella moellendorffii 1014  
evm.model.supercontig_30.68 PAC:16417019 Carica papaya 811  
27967.m000046 B9T7E5 PAC:16799664 Ricinus communis 713  
Cucsa.049050.1 PAC:16953977 Cucumis sativus 839  
Cucsa.049050.2 PAC:16953978 Cucumis sativus 835  
orange1.1g003809m PAC:18138751 Citrus sinensis 794  
AT5G44635.1 F4KAB8 PAC:19669092 Arabidopsis thaliana 831  
Thhalv10000779m V4N2W8 PAC:20202982 Eutrema salsugineum 830  
Ciclev10014269m V4TMU6 PAC:20818684 Citrus clementina 834  
Lus10036244 PAC:23169387 Linum usitatissimum 831  
Lus10038384 PAC:23158301 Linum usitatissimum 827  
Potri.001G074000.1 PAC:27044223 Populus trichocarpa 834  
Potri.003G157000.1 PAC:26996623 Populus trichocarpa 466  
Gorai.005G268500.1 A0A0D2Q091 PAC:26802417 Gossypium raimondii 727  
15102 I0YYD7 PAC:27386637 Coccomyxa subellipsoidea C-169 690  
211868 PAC:27343186 Micromonas pusilla CCMP1545 892  
113356 C1FDV1 PAC:27399339 Micromonas sp RCC299 907  
39655 A4RR24 PAC:27417983 Ostreococcus lucimarinus 841  
Thecc1EG005965t8 A0A061DXK5 PAC:27460158 Theobroma cacao 625  
Thecc1EG005965t4 A0A061DWM3 PAC:27460156 Theobroma cacao 655  
Thecc1EG005965t6 A0A061DVJ0 PAC:27460157 Theobroma cacao 628  
Thecc1EG005965t7 A0A061DVS8 PAC:27460159 Theobroma cacao 570  
Thecc1EG005965t9 A0A061DWM8 PAC:27460160 Theobroma cacao 567  
Thecc1EG005965t1 A0A061DVI6 PAC:27460153 Theobroma cacao 826  
Thecc1EG005965t5 A0A061E3G5 PAC:27460154 Theobroma cacao 713  
Thecc1EG005965t2 A0A061DVS5 PAC:27460152 Theobroma cacao 827  
Thecc1EG005965t3 A0A061DXK1 PAC:27460155 Theobroma cacao 710  
Migut.H01418.1.p PAC:28953217 Mimulus guttatus 753  
Araha.19882s0001.1.p PAC:28863480 Arabidopsis halleri 831  
Cagra.1562s0003.1.p PAC:28904655 Capsella grandiflora 830  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            19896182
            19910535
            22841721
            17506634