1 Contains
| DB identifier | Type | Name |
|---|---|---|
| IPR015421 | Domain | Pyridoxal phosphate-dependent transferase, major region, subdomain 1 |
| Type: | Family | Name: | Ornithine aminotransferase |
| Description: | Ornithine aminotransferase catalyses the conversion of L-ornithine and a 2-oxo acid to L-glutamate 5-semialdehyde and an L-amino acid. This enzyme is found in low-GC bacteria, where it is responsible for the fourth step in arginine biosynthesis, and in the mitochondrial matrix of eukaryotes, where it controls L-ornithine levels in tissues. In human hereditary ornithine aminotransferase deficiency, the elevated levels of intraocular concentrations of ornithine are responsible for gyrate atrophy, which affects the CNS and peripheral nervous system []. | Short Name: | Orn_aminotrans |
| DB identifier | Type | Name |
|---|---|---|
| IPR015421 | Domain | Pyridoxal phosphate-dependent transferase, major region, subdomain 1 |
