Protein Domain : IPR010038

Type:  Family Name:  MoaD, archaeal-type
Description:  Members of this family appear to be mainly archaeal and bacterial versions of MoaD, subunit 1 of molybdopterin converting factor. Small archaeal modifier protein 1 (SAM1) is a member of this family and it is involved in protein tagging in an ubiquitin-like system from archaea known as SAMPylation []. It is not known whether it is implicated in the targeting of proteins to the proteasome for degradation []. SAM1 is also essential for MoCo-dependent dimethyl sulphoxide reductase activity, suggesting that it functions in the sulphur-containing molybdenum cofactor (MoCo) biosynthesis [].SAM proteins, as Ub/Ubl proteins, have a beta-grasp fold common to a growing superfamily of proteins involved in diverse functions. Among these functions, sulphur activation for the biosynthesis of thiamine, tungsten and molybdenum cofactors bears striking resemblance to the activation of Ub/Ubl []. Short Name:  MoaD_arc-typ

0 Child Features

1 Contains

DB identifier Type Name
IPR016155 Domain Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp

1 Cross References

Identifier
TIGR01687

0 Found In

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Type Name
IPR003749 Family ThiamineS/Molybdopterin converting factor subunit 1

7 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
138571 D8TFN3 PAC:15401417 Selaginella moellendorffii 91  
89945 D8RBE3 PAC:15413247 Selaginella moellendorffii 91  
12278 I0Z8E1 PAC:27393579 Coccomyxa subellipsoidea C-169 83  
Cre08.g382545.t1.1 A8JJB2 PAC:30773615 Chlamydomonas reinhardtii 83  
Cz12g08130.t1 PAC:38240388 Chromochloris zofingiensis 83  
Bobra.0026s0023.1.p PAC:40707890 Botryococcus braunii 83  
Vocar.0042s0047.1.p PAC:32892094 Volvox carteri 83  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            20547064
            20054389
            21368171
            17064282