1 Contains
DB identifier | Type | Name |
---|---|---|
IPR020569 | Conserved_site | Uncharacterised protein family UPF0029, Impact, conserved site |
Type: | Domain | Name: | Impact, N-terminal |
Description: | The Impact protein is a translational regulator that ensures constant high levels of translation under amino acid starvation. It acts by interacting with Gcn1/Gcn1L1, thereby preventing activation of Gcn2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. It is evolutionary conserved from eukaryotes to archaea []. This entry represents the N-terminal domain of the Impact proteins. | Short Name: | Impact_N |
DB identifier | Type | Name |
---|---|---|
IPR020569 | Conserved_site | Uncharacterised protein family UPF0029, Impact, conserved site |