Protein Domain : IPR012846

Type:  Family Name:  Acetolactate synthase, large subunit, biosynthetic
Description:  Two groups of proteins form acetolactate from two molecules of pyruvate. The type of acetolactate synthase described in this entry also catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched chain amino acid biosynthesis; it is therefore also termed acetohydroxyacid synthase. In bacteria, this catalytic chain is associated with a smaller regulatory chain in an alpha2/beta2 heterotetramer. Acetolactate synthase is a thiamine pyrophosphate enzyme. In this type, FAD and Mg++ are also found. Several isozymes of this enzyme are found in Escherichia coli(strain K12), one of which contains a frameshift in the large subunit gene and is not expressed. Short Name:  Acetolactate_synth_lsu
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0 Child Features

4 Contains

DB identifier Type Name
IPR011766 Domain Thiamine pyrophosphate enzyme, C-terminal TPP-binding
IPR012000 Domain Thiamine pyrophosphate enzyme, central domain
IPR012001 Domain Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain
IPR000399 Conserved_site TPP-binding enzyme, conserved site

1 Cross References

Identifier
TIGR00118

0 Found In

5 GO Annotations

GO Term Gene Name
GO:0000287 IPR012846
GO:0003984 IPR012846
GO:0030976 IPR012846
GO:0050660 IPR012846
GO:0009082 IPR012846

5 Ontology Annotations

GO Term Gene Name
GO:0000287 IPR012846
GO:0003984 IPR012846
GO:0030976 IPR012846
GO:0050660 IPR012846
GO:0009082 IPR012846

0 Parent Features

529 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
269200 D8SUH1 PAC:15415544 Selaginella moellendorffii 601  
90109 D8RCB1 PAC:15410229 Selaginella moellendorffii 600  
evm.model.supercontig_13.109 PAC:16407613 Carica papaya 664  
30147.m014497 B9RAF1 PAC:16820505 Ricinus communis 660  
Cucsa.157320.1 A0A0A0LU17 PAC:16964984 Cucumis sativus 665  
orange1.1g048725m A0A067E0B2 PAC:18094679 Citrus sinensis 661  
AT3G48560.1 P17597 PAC:19662827 Arabidopsis thaliana 670  
Thhalv10010177m V4L5S0 PAC:20207229 Eutrema salsugineum 662  
Ciclev10030907m V4T9Z7 PAC:20802870 Citrus clementina 661  
Ciclev10007130m V4S469 PAC:20790183 Citrus clementina 643  
Lus10035207 PAC:23162488 Linum usitatissimum 490  
Lus10016751 PAC:23149165 Linum usitatissimum 660  
Potri.015G097200.1 B9IFC5 PAC:27017467 Populus trichocarpa 650  
Potri.012G098300.1 A0A2K1YBJ2 PAC:27050794 Populus trichocarpa 658  
Gorai.005G016600.1 A0A0D2PLF8 PAC:26801766 Gossypium raimondii 659  
Gorai.011G141100.1 A0A0D2USX1 PAC:26811202 Gossypium raimondii 658  
37553 I0YS85 PAC:27386112 Coccomyxa subellipsoidea C-169 629  
36361 C1N612 PAC:27342367 Micromonas pusilla CCMP1545 686  
88562 C1EI66 PAC:27400920 Micromonas sp RCC299 609  
51596 A4S8I1 PAC:27417285 Ostreococcus lucimarinus 610  
Thecc1EG020010t1 A0A061EIJ0 PAC:27452484 Theobroma cacao 659  
Migut.D01268.1.p A0A022RVT2 PAC:28928099 Mimulus guttatus 655  
Migut.I00533.1.p A0A022Q9C5 PAC:28931403 Mimulus guttatus 659  
Araha.0028s0013.1.p PAC:28854331 Arabidopsis halleri 666  
Araha.11756s0428.1.p PAC:28856531 Arabidopsis halleri 571  
Cagra.0134s0005.1.p PAC:28915257 Capsella grandiflora 667  
Glyma.06G169700.1.p I1KC25 PAC:30554204 Glycine max 656  
Glyma.13G241000.1.p D2DJQ3 PAC:30504097 Glycine max 645  
Glyma.15G072500.1.p I1MEG7 PAC:30497053 Glycine max 653  
Glyma.04G196100.1.p A0A0R0KAA8 PAC:30488669 Glycine max 639  

0 Publications