Type: | Family | Name: | Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase |
Description: | This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase I/ nucleotide pyrophosphatase (nppase). These enzymes catalyse the cleavage of phosphodiester and phosphosulphate bonds in NAD, deoxynucleotides and nucleotide sugars []. Another member of this family isATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity [].The alignment encompasses the active site [, ].Also present within this family is 60 kDa Ca2+-ATPase from Myroides odoratus[].This signature also hits a number of ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. | Short Name: | Phosphodiest/P_Trfase |