Protein Domain : IPR008656

Type:  Family Name:  Inositol-tetrakisphosphate 1-kinase
Description:  This entry represents inositol-tetrakisphosphate 1-kinase, which is also called inositol 1,3,4-trisphosphate 5/6-kinase. Inositol-tetrakisphosphate 1-kinase can phosphorylate various inositol polyphosphates, such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylation of Ins(3,4,5,6)P4 at position 1 forms Ins(1,3,4,5,6)P5 which has regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels. Phosphorylation of Ins(1,3,4)P3 on O-5 and O-6 forms Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway [, , , , ]. Short Name:  Inositol_tetrakis-P_1-kinase
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1 Child Features

DB identifier Type Name
IPR017418 Family Inositol-tetrakisphosphate 1-kinase 4

1 Contains

DB identifier Type Name
IPR011761 Domain ATP-grasp fold

2 Cross Referencess

Identifier
PF05770
PIRSF038186

0 Found In

7 GO Annotations

GO Term Gene Name
GO:0000287 IPR008656
GO:0005524 IPR008656
GO:0047325 IPR008656
GO:0052725 IPR008656
GO:0052726 IPR008656
GO:0032957 IPR008656
GO:0005622 IPR008656

7 Ontology Annotations

GO Term Gene Name
GO:0000287 IPR008656
GO:0005524 IPR008656
GO:0047325 IPR008656
GO:0052725 IPR008656
GO:0052726 IPR008656
GO:0032957 IPR008656
GO:0005622 IPR008656

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
232261 D8RSZ8 PAC:15418206 Selaginella moellendorffii 316  
422909 D8SJY4 PAC:15422380 Selaginella moellendorffii 436  
429562 D8T6K7 PAC:15417705 Selaginella moellendorffii 160  
evm.model.supercontig_106.26 PAC:16405189 Carica papaya 351  
evm.model.supercontig_160.11 PAC:16410141 Carica papaya 357  
evm.model.supercontig_2592.1 PAC:16415024 Carica papaya 361  
evm.model.supercontig_26.211 PAC:16415152 Carica papaya 500  
30042.m000491 B9SSZ4 PAC:16816063 Ricinus communis 491  
30073.m002287 B9S244 PAC:16816870 Ricinus communis 343  
30170.m013637 B9R6S4 PAC:16821486 Ricinus communis 355  
Cucsa.318600.1 PAC:16977189 Cucumis sativus 326  
Cucsa.312950.1 PAC:16976937 Cucumis sativus 333  
Cucsa.321950.1 PAC:16977655 Cucumis sativus 350  
Cucsa.160960.2 PAC:16965439 Cucumis sativus 283  
Cucsa.160960.1 A0A0A0LRX7 PAC:16965438 Cucumis sativus 347  
Cucsa.218560.1 PAC:16969687 Cucumis sativus 453  
orange1.1g024667m A0A067GNR4 PAC:18108112 Citrus sinensis 264  
orange1.1g024655m A0A067GNR4 PAC:18108113 Citrus sinensis 264  
orange1.1g024689m A0A067GNR4 PAC:18108114 Citrus sinensis 264  
orange1.1g027466m A0A067H1B7 PAC:18108115 Citrus sinensis 223  
orange1.1g027695m A0A067GRR9 PAC:18108116 Citrus sinensis 220  
orange1.1g027665m A0A067GRR9 PAC:18108118 Citrus sinensis 220  
orange1.1g019600m A0A067GRQ8 PAC:18108108 Citrus sinensis 338  
orange1.1g027674m A0A067GRR9 PAC:18108117 Citrus sinensis 220  
orange1.1g019652m A0A067H1B3 PAC:18108109 Citrus sinensis 337  
orange1.1g023408m A0A067H0W8 PAC:18108110 Citrus sinensis 282  
orange1.1g024006m A0A067H0X3 PAC:18108111 Citrus sinensis 274  
orange1.1g047754m A0A067EMQ3 PAC:18093676 Citrus sinensis 330  
orange1.1g021495m PAC:18129138 Citrus sinensis 311  
orange1.1g022919m PAC:18129139 Citrus sinensis 290  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8662638
            17616525
            11533064
            11909533
            12925536