Type: | Domain | Name: | WASH complex subunit 7, central domain |
Description: | This entry represents the central, conserved region of WASH complex subunit 7 (WASH7) []. The WASH complex is present at the surface of endosomes and recruits and activates the Arp2/3 complex to induce mediatedactin nucleation. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting [, ]. | Short Name: | WASH-7_central |