Protein Domain : IPR004733

Type:  Family Name:  Phosphoribosylformylglycinamidine cyclo-ligase
Description:  The purine biosynthetic pathway in procaryotes enlists eleven enzymes, six of which use ATP. Enzymes 5 and 6 of this pathway, formylglycinamide ribonucleotide (FGAR) amidotransferase (PurL) and aminoimidazole ribonucleotide (AIR) synthetase (PurM or AIRS) utilise ATP to activate the oxygen of an amide within their substrate toward nucleophilic attack by a nitrogen. PurM (also known as phosphoribosyl-aminoimidazole synthetase or phosphoribosylformylglycinamidine cyclo-ligase) uses the product of PurL, formylglycinamidine ribonucleotide (FGAM) and ATP to make AIR, ADP and P(i) [, ]. Short Name:  PurM_cligase
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0 Child Features

1 Contains

DB identifier Type Name
IPR010918 Domain AIR synthase-related protein, C-terminal domain

2 Cross Referencess

Identifier
TIGR00878
MF_00741

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004641 IPR004733
GO:0006189 IPR004733
GO:0005737 IPR004733

3 Ontology Annotations

GO Term Gene Name
GO:0004641 IPR004733
GO:0006189 IPR004733
GO:0005737 IPR004733

0 Parent Features

521 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
92321 D8RFS4 PAC:15417623 Selaginella moellendorffii 389  
117177 D8SHG9 PAC:15403326 Selaginella moellendorffii 401  
evm.model.supercontig_8.158 PAC:16426439 Carica papaya 405  
30076.m004686 B9RNH2 PAC:16817295 Ricinus communis 394  
Cucsa.304190.4 PAC:16976019 Cucumis sativus 292  
Cucsa.304190.3 PAC:16976018 Cucumis sativus 308  
Cucsa.304190.1 A0A0A0KNN8 PAC:16976016 Cucumis sativus 402  
Cucsa.304190.2 PAC:16976017 Cucumis sativus 391  
AT3G55010.1 Q05728 PAC:19662685 Arabidopsis thaliana 389  
AT3G55010.2 Q05728 PAC:19662686 Arabidopsis thaliana 389  
Thhalv10010529m V4NFP5 PAC:20207779 Eutrema salsugineum 334  
Thhalv10010436m V4LR19 PAC:20207778 Eutrema salsugineum 393  
Thhalv10018710m V4KCD6 PAC:20191818 Eutrema salsugineum 380  
Lus10039497 PAC:23165303 Linum usitatissimum 299  
Lus10040931 PAC:23179742 Linum usitatissimum 383  
Lus10009823 PAC:23180180 Linum usitatissimum 356  
Potri.002G198600.1 PAC:27020116 Populus trichocarpa 462  
Potri.002G198600.2 PAC:27020117 Populus trichocarpa 332  
Potri.014G123000.1 B9I9L4 PAC:27034842 Populus trichocarpa 395  
Gorai.007G124500.2 A0A0D2TDU8 PAC:26778482 Gossypium raimondii 400  
Gorai.007G124500.1 A0A0D2TDU8 PAC:26778481 Gossypium raimondii 400  
13206 I0Z4D0 PAC:27389848 Coccomyxa subellipsoidea C-169 382  
Thecc1EG004771t1 A0A061DT32 PAC:27432705 Theobroma cacao 416  
Migut.M01874.1.p A0A022PUE2 PAC:28949710 Mimulus guttatus 402  
Araha.2258s0015.1.p PAC:28844259 Arabidopsis halleri 388  
Cagra.1742s0018.1.p PAC:28910584 Capsella grandiflora 383  
Glyma.05G192900.1.p I1K506 PAC:30523653 Glycine max 387  
Glyma.08G001000.1.p I1KNV7 PAC:30536931 Glycine max 391  
Brara.G01655.1.p A0A397YLP8 PAC:30635028 Brassica rapa FPsc 385  
Brara.I03766.1.p A0A397Y925 PAC:30642760 Brassica rapa FPsc 388  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10508786
            3015935