Protein Domain : IPR004538

Type:  Family Name:  Haemolysin A /rRNA methyltransferase TlyA
Description:  Haemolysins are exotoxins that attack blood cell membranes and cause cell rupture. The mechanism of action is not well defined. Haemolysin A is induced by sodium ribonucleate, and is produced by pathogenic bacterial strains. Haemolysin A from Treponema hyodysenteriaecauses swine dysentery []. The homologous protein from Mycobacterium tuberculosis is known as 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA and exhibits hemolytic activity in vitro. It catalyses the 2'-O-methylation at nucleotides C1409 in 16S rRNA and C1920 in 23S rRNA [, , ]. Short Name:  Haemolysin_A/TlyA
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0 Child Features

2 Contains

DB identifier Type Name
IPR002942 Domain RNA-binding S4 domain
IPR002877 Domain Ribosomal RNA methyltransferase FtsJ domain

2 Cross Referencess

Identifier
PIRSF005578
TIGR00478

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0003723 IPR004538

1 Ontology Annotations

GO Term Gene Name
GO:0003723 IPR004538

0 Parent Features

441 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
47053 D8T9M6 PAC:15416332 Selaginella moellendorffii 243  
57075 D8RVF3 PAC:15423475 Selaginella moellendorffii 252  
30178.m000878 B9SMR6 PAC:16822852 Ricinus communis 312  
Cucsa.387890.1 A0A0A0KA33 PAC:16982776 Cucumis sativus 296  
AT3G25470.1 Q9LSV5 PAC:19662177 Arabidopsis thaliana 301  
Thhalv10002617m V4MXB1 PAC:20196405 Eutrema salsugineum 304  
Ciclev10015989m V4TL63 PAC:20817098 Citrus clementina 316  
Ciclev10018050m V4UFW6 PAC:20815989 Citrus clementina 233  
Lus10008746 PAC:23169002 Linum usitatissimum 394  
Lus10002144 PAC:23181297 Linum usitatissimum 326  
Potri.014G175500.3 A0A2K1XXI1 PAC:27034439 Populus trichocarpa 319  
Potri.014G175500.5 PAC:27034442 Populus trichocarpa 255  
Potri.014G175500.1 PAC:27034438 Populus trichocarpa 330  
Potri.014G175500.2 A0A2K1XXJ6 PAC:27034440 Populus trichocarpa 313  
Gorai.007G161200.1 A0A0D2SE89 PAC:26778707 Gossypium raimondii 304  
28915 I0YYU2 PAC:27386741 Coccomyxa subellipsoidea C-169 258  
205021 PAC:27348120 Micromonas pusilla CCMP1545 254  
71072 C1E4A5 PAC:27400567 Micromonas sp RCC299 246  
12600 A4RYM6 PAC:27418541 Ostreococcus lucimarinus 245  
Thecc1EG002613t2 A0A061DM09 PAC:27431691 Theobroma cacao 261  
Thecc1EG002613t1 A0A061DLQ1 PAC:27431690 Theobroma cacao 290  
Migut.D00775.1.p A0A022S2E4 PAC:28926751 Mimulus guttatus 328  
Araha.55501s0001.1.p PAC:28851366 Arabidopsis halleri 302  
Cagra.1183s0009.1.p PAC:28897742 Capsella grandiflora 302  
Glyma.07G124200.2.p A0A0R0J3E4 PAC:30491550 Glycine max 286  
Glyma.07G124200.1.p K7L0Y9 PAC:30491549 Glycine max 315  
Glyma.03G097100.1.p K7KE27 PAC:30516434 Glycine max 315  
Glyma.03G097100.2.p A0A0R0KGU8 PAC:30516437 Glycine max 251  
Glyma.03G097100.5.p A0A0R0KGU4 PAC:30516438 Glycine max 216  
Glyma.03G097100.4.p A0A0R0KNI6 PAC:30516436 Glycine max 280  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1730486
            9611795
            20854656
            21443791