3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0016651 | IPR001133 |
| GO:0042773 | IPR001133 |
| GO:0055114 | IPR001133 |
| Type: | Family | Name: | NADH-ubiquinone oxidoreductase chain 4L/K |
| Description: | NADH:ubiquinone oxidoreductase (complex I) () is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) []. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins []. This entry represents NADH:ubiquinone oxidoreductase, chain 4L, as well as NADH-quinone oxidoreductase (). In eukaryotes, these enzymes are usually found in either mitochondria or chloroplasts as part of the respiratory-chain NADH dehydrogenase (also known as complex I or NADH-ubiquinone oxidoreductase), an oligomeric enzymatic complex []. However, they are also found in bacteria [] and archaea [] where they are annotated as NuoK subunit. | Short Name: | NADH_UbQ_OxRdtase_chain4L/K |
| GO Term | Gene Name |
|---|---|
| GO:0016651 | IPR001133 |
| GO:0042773 | IPR001133 |
| GO:0055114 | IPR001133 |
