Protein Domain : IPR010227

Type:  Family Name:  NADH-quinone oxidoreductase, chain M/4
Description:  NADH:ubiquinone oxidoreductase (complex I) () is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) []. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins []. This entry contains members of the complex I subunit 4 family. Members of this family include the 13th structural gene, M, of bacterial NADH dehydrogenase I (based on Escherichia coli), as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. Short Name:  NADH_Q_OxRdtase_chainM/4
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1 Child Features

DB identifier Type Name
IPR022997 Family NADH-quinone oxidoreductase chain 4

2 Contains

DB identifier Type Name
IPR001750 Domain NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit
IPR000260 Domain NADH:ubiquinone oxidoreductase chain 4, N-terminal

1 Cross References

Identifier
TIGR01972

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0008137 IPR010227
GO:0042773 IPR010227
GO:0055114 IPR010227

3 Ontology Annotations

GO Term Gene Name
GO:0008137 IPR010227
GO:0042773 IPR010227
GO:0055114 IPR010227

1 Parent Features

DB identifier Type Name
IPR003918 Family NADH:ubiquinone oxidoreductase

332 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
137786 D8TE48 PAC:15422313 Selaginella moellendorffii 524  
Cucsa.245810.1 PAC:16971391 Cucumis sativus 249  
ATMG00580.1 G1C2U9 PAC:19643646 Arabidopsis thaliana 495  
ATCG01050.1 PAC:19637969 Arabidopsis thaliana 506  
Ciclev10010880m V4TB62 PAC:20796223 Citrus clementina 243  
Araha.11756s0376.1.p PAC:28856497 Arabidopsis halleri 505  
Cagra.5120s0013.1.p PAC:28904239 Capsella grandiflora 502  
Medtr4g006120.1 G7JVM1 PAC:31108534 Medicago truncatula 573  
Medtr4g050950.1 G7JFZ4 PAC:31115242 Medicago truncatula 498  
Medtr7g021720.1 G7KTU3 PAC:31082976 Medicago truncatula 587  
Medtr7g075220.1 G7L0B6 PAC:31077339 Medicago truncatula 994  
Medtr0002s0170.1 A0A072TKF2 PAC:31084765 Medicago truncatula 425  
SapurV1A.5364s0020.1.p PAC:31433108 Salix purpurea 313  
Traes_1AL_C9C8DBE4D.1 PAC:31774856 Triticum aestivum 339  
Traes_1AS_3A92B17F0.2 PAC:31908803 Triticum aestivum 500  
Traes_1BL_3A92B17F0.2 PAC:31837564 Triticum aestivum 500  
Traes_1BS_1182C63E2.1 PAC:31973354 Triticum aestivum 482  
Traes_1DS_3A92B17F0.2 PAC:32007484 Triticum aestivum 500  
Traes_1DS_B2FF21D13.2 PAC:31904031 Triticum aestivum 324  
Traes_2AL_3A92B17F0.2 PAC:31969761 Triticum aestivum 500  
Traes_2AS_3A92B17F0.2 PAC:32017268 Triticum aestivum 500  
Traes_2BL_3A92B17F02.2 PAC:31869586 Triticum aestivum 500  
Traes_2BL_3A92B17F0.2 PAC:31774362 Triticum aestivum 500  
Traes_3AS_3A92B17F0.2 PAC:31957589 Triticum aestivum 500  
Traes_3DL_3A92B17F0.2 PAC:31800932 Triticum aestivum 500  
Traes_3DS_7A47E4C5F.1 PAC:31866299 Triticum aestivum 210  
Traes_4AL_3A92B17F0.2 PAC:31802806 Triticum aestivum 500  
Traes_4AS_A4821092E1.1 PAC:31876773 Triticum aestivum 284  
Traes_4AS_A4821092E.1 PAC:31958737 Triticum aestivum 284  
Traes_4BL_3A92B17F0.2 PAC:31766505 Triticum aestivum 500  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1470679
            10940377
            18394423