1 Parent Features
DB identifier | Type | Name |
---|---|---|
IPR015507 | Family | Ribosomal RNA large subunit methyltransferase E |
Type: | Family | Name: | AdoMet-dependent rRNA methyltransferase, Spb1 |
Description: | Spb1 is an adoMet-dependent rRNA methyltransferase required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit []. In Saccharomyces cerevisiae, it specifically methylates the guanosine in position 2922 of the 25S rRNA at the stage of 27S pre-rRNA maturation []. It interacts with the snoRNA-associated proteins Nop1 and Nop58 []. FTSJ3, Spb1 homologue in humans, is associates with NIP7 (involved in the biogenesis of 40S subunit) and functions in pre-rRNA processing []. | Short Name: | Spb1 |
DB identifier | Type | Name |
---|---|---|
IPR015507 | Family | Ribosomal RNA large subunit methyltransferase E |