Protein Domain : IPR013536

Type:  Domain Name:  WLM domain
Description:  The WLM (WSS1-like metalloprotease) domain is a globular domain related to the zincin-like superfamily of Zn-dependent peptidase. Since the WLM domaincontains all known active site residues of zincins, it is predicted to be a catalytically active peptidase domain. The WLM domain is a eukaryotic domainrepresented in plants, fungi, Plasmodium, and kinetoplastids. By contrast, it is absent in animals, Cryptosporidium, and Microsporidia, suggesting that ithas been lost on multiple occasions during the evolution of eukaryotes. The WLM domain is found either in stand-alone form or in association with otherdomains such as the RanBP2 zinc finger , the ubiquitin domain, or the PUB/PUG domain. This domain could functionas a specific de-SUMOylating domain of distinct protein complexes in the nucleus and the cytoplasm []. It has been suggested to form a segregated alpha/beta structure with eight helices and five strands. Proteins containign this domain include yeast WSS1 (a weak suppressor of the Ub-related protein SMT3), and various putative metalloproteases from plant and fungal species. Short Name:  WLM_dom

0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF08325
PS51397

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
165588 D8QVB3 PAC:15414387 Selaginella moellendorffii 321  
evm.model.supercontig_12.172 PAC:16406717 Carica papaya 386  
evm.model.supercontig_132.47 PAC:16408143 Carica papaya 575  
29748.m000378 B9SAJ5 PAC:16807773 Ricinus communis 326  
29620.m000545 B9SSI5 PAC:16803798 Ricinus communis 594  
29629.m001400 B9S9V1 PAC:16803981 Ricinus communis 404  
Cucsa.390860.1 A0A0A0K3J6 PAC:16982922 Cucumis sativus 414  
Cucsa.390860.2 A0A0A0K3J6 PAC:16982923 Cucumis sativus 414  
Cucsa.139760.1 PAC:16963414 Cucumis sativus 690  
orange1.1g019784m A0A067DFN0 PAC:18111028 Citrus sinensis 336  
orange1.1g020589m A0A067DRJ7 PAC:18111029 Citrus sinensis 324  
orange1.1g022290m A0A067DJC3 PAC:18111030 Citrus sinensis 299  
orange1.1g025948m A0A067DST7 PAC:18111031 Citrus sinensis 245  
orange1.1g019774m A0A067DFN0 PAC:18111027 Citrus sinensis 336  
orange1.1g006021m A0A067EWW0 PAC:18111874 Citrus sinensis 664  
orange1.1g006017m A0A067EWW0 PAC:18111875 Citrus sinensis 664  
orange1.1g010667m A0A067F0F1 PAC:18111877 Citrus sinensis 504  
orange1.1g008299m A0A067EWR4 PAC:18111876 Citrus sinensis 570  
orange1.1g006022m A0A067EWW0 PAC:18111873 Citrus sinensis 664  
orange1.1g038987m A0A067F6G6 PAC:18114030 Citrus sinensis 316  
AT5G35690.1 Q8VYQ7 PAC:19669435 Arabidopsis thaliana 603  
AT1G55915.1 Q0WPG7 PAC:19655252 Arabidopsis thaliana 404  
Thhalv10003861m V4L0I1 PAC:20200074 Eutrema salsugineum 600  
Thhalv10003827m V4KPK8 PAC:20200073 Eutrema salsugineum 621  
Thhalv10003884m V4KT74 PAC:20200075 Eutrema salsugineum 587  
Thhalv10011589m PAC:20184540 Eutrema salsugineum 366  
Ciclev10027497m V4SUV5 PAC:20800516 Citrus clementina 336  
Ciclev10010194m V4UTB9 PAC:20793839 Citrus clementina 300  
Ciclev10014523m V4U4P9 PAC:20819082 Citrus clementina 664  
Lus10002262 PAC:23153446 Linum usitatissimum 583  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15483401