Protein Domain : IPR010431

Type:  Family Name:  Fascin
Description:  This entry represents fascin (FSCN) and its homologues, including FSCN1/2/3 from mammals and protein singed from fruit flies. Fascin is a globular actin cross-linking protein, which functions in forming parallel actin bundles in cell protrusions that are key specialisations of the plasma membrane for environmental guidance and cell migration []. Human FSCN1 organises filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Overexpression of fascin has been linked to a more aggressive clinical course of cancer []. Short Name:  Fascin
Paste the following link

1 Child Features

DB identifier Type Name
IPR024703 Family Fascin, metazoans

1 Contains

DB identifier Type Name
IPR022768 Domain Fascin domain

1 Cross References

Identifier
PTHR10551

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0051015 IPR010431
GO:0007015 IPR010431

2 Ontology Annotations

GO Term Gene Name
GO:0051015 IPR010431
GO:0007015 IPR010431

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
404183 D8QUI8 PAC:15407877 Selaginella moellendorffii 505  
126827 D8SWV9 PAC:15412943 Selaginella moellendorffii 329  
24801 D8SWU2 PAC:15421364 Selaginella moellendorffii 295  
426582 D8SWU6 PAC:15408907 Selaginella moellendorffii 528  
evm.model.supercontig_20.222 PAC:16413029 Carica papaya 474  
evm.model.supercontig_55.63 PAC:16422631 Carica papaya 413  
evm.model.supercontig_66.87 PAC:16424655 Carica papaya 498  
29810.m000145 B9T5P7 PAC:16809369 Ricinus communis 515  
29908.m005994 B9RJG5 PAC:16812817 Ricinus communis 506  
27905.m000074 B9T772 PAC:16799469 Ricinus communis 172  
27905.m000073 B9T771 PAC:16799468 Ricinus communis 507  
27889.m000171 B9T4P0 PAC:16799397 Ricinus communis 161  
27889.m000173 B9T4P2 PAC:16799399 Ricinus communis 318  
Cucsa.104180.1 A0A0A0KLU4 PAC:16959158 Cucumis sativus 530  
Cucsa.104180.2 PAC:16959159 Cucumis sativus 479  
orange1.1g020317m A0A067D6M3 PAC:18123964 Citrus sinensis 327  
orange1.1g024471m A0A067DA88 PAC:18123965 Citrus sinensis 267  
orange1.1g020265m A0A067D663 PAC:18123963 Citrus sinensis 328  
orange1.1g043245m A0A067DA16 PAC:18116965 Citrus sinensis 202  
orange1.1g032916m A0A067GQE1 PAC:18108386 Citrus sinensis 130  
orange1.1g009560m A0A067EZY2 PAC:18139354 Citrus sinensis 532  
orange1.1g046395m A0A067DW05 PAC:18103080 Citrus sinensis 535  
orange1.1g009475m A0A067DZK0 PAC:18103082 Citrus sinensis 534  
orange1.1g010600m A0A067DVL1 PAC:18103083 Citrus sinensis 506  
orange1.1g019395m A0A067E725 PAC:18103085 Citrus sinensis 341  
orange1.1g013777m A0A067E7Z9 PAC:18103084 Citrus sinensis 436  
Ciclev10000913m V4SHW0 PAC:20786166 Citrus clementina 509  
Ciclev10025463m PAC:20802171 Citrus clementina 492  
Ciclev10026955m V4UPG7 PAC:20802083 Citrus clementina 498  
Ciclev10025415m V4SR38 PAC:20800896 Citrus clementina 506  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16002322