Type: | Domain | Name: | Anaphase-promoting complex subunit 2, C-terminal |
Description: | The anaphase-promoting complex (APC) or cyclosome is a multi-subunit E3 protein ubiquitin ligase that regulates important events in mitosis, such as the initiation of anaphase and exit from telophase. The APC, in conjunction with other enzymes, assembles multi-ubiquitin chains on a variety of regulatory proteins, thereby targeting them for proteolysis by the 26S proteasome.This entry represents a domain found in the C terminus of APC subunit 2. | Short Name: | APC_su2_C |