Type: | Domain | Name: | Phosducin, thioredoxin-like domain |
Description: | The outer and inner segments of vertebrate rod photoreceptor cells contain phosducin, a soluble phosphoprotein that complexes with the beta/gamma-subunits of the GTP-bindingprotein, transducin. Light-induced changes in cyclic nucleotide levels modulate the phosphorylation of phosducin by protein kinase A []. The protein is thought to participate in the regulation ofvisual phototransduction or in the integration of photo-receptor metabolism. Similar proteins have been isolated from the pineal gland and it is believed that the functionalrole of the protein is the same in both retina and pineal gland [].This entry represents a domain found in members of the phosducin family. This domain has a thioredoxin-like fold []. | Short Name: | Phosducin_thioredoxin-like_dom |