| Type: | Family | Name: | RNA polymerase II holoenzyme, cyclin-like subunit Ssn8, fungi |
| Description: | This entry represents the cyclin-like subunit Ssn8 (also known as Fcc1 or Ume3) of the SRB8-11 complex from fungi. The SRB8-11 complex is a regulatory module of the Mediator complex, which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription [, ].Ssn8 shares homology with human cyclin C []. It is likely to form a cdk-cyclin pair with Ssn3 (a cyclin-dependent protein kinase) in the RNAPII holoenzyme, contributing to transcriptional repression of diversely regulated genes []. It is required for efficient induction and execution of meiotic program []. | Short Name: | Cyclin-like_Ssn8 |
