Protein Domain : IPR007719

Type:  Family Name:  Phytochelatin synthase
Description:  This entry represents plant phytochelatin synthases (also known as glutathione gamma-glutamylcysteinyltransferase; ), which is involved in the synthesis of phytochelatins (PC) and homophytochelatins (hPC), the heavy-metal-binding peptides of plants. This enzyme is required for detoxification of heavy metals such as cadmium and arsenate. The N-terminal region of phytochelatin synthase contains the active site, as well as four highly conserved cysteine residues that appear to play an important role in heavy-metal-induced phytochelatin catalysis. The C-terminal region is rich in cysteines, and may act as a metal sensor, whereby the Cys residues bind cadmium ions to bring them into closer proximity and transferring them to the activation site in the N-terminal catalytic domain []. The C-terminal region displays homology to the functional domains of metallothionein and metallochaperone. Short Name:  Phytochelatin_synthase
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF05023
PS51443

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0016756 IPR007719
GO:0046872 IPR007719
GO:0010038 IPR007719
GO:0046938 IPR007719

4 Ontology Annotations

GO Term Gene Name
GO:0016756 IPR007719
GO:0046872 IPR007719
GO:0010038 IPR007719
GO:0046938 IPR007719

0 Parent Features

790 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
98967 D8RQU0 PAC:15417517 Selaginella moellendorffii 472  
evm.model.supercontig_165.31 PAC:16410372 Carica papaya 503  
evm.model.supercontig_165.32 PAC:16410373 Carica papaya 496  
28492.m000470 B9SV16 PAC:16800950 Ricinus communis 502  
Cucsa.132150.1 PAC:16962502 Cucumis sativus 150  
Cucsa.348990.6 PAC:16979708 Cucumis sativus 468  
Cucsa.348990.4 PAC:16979706 Cucumis sativus 468  
Cucsa.348980.1 A0A0A0KC11 PAC:16979702 Cucumis sativus 487  
Cucsa.348990.1 PAC:16979703 Cucumis sativus 468  
orange1.1g011053m A0A067F2S1 PAC:18113937 Citrus sinensis 494  
orange1.1g010722m A0A067EZ47 PAC:18113905 Citrus sinensis 503  
orange1.1g009934m A0A067FB41 PAC:18113904 Citrus sinensis 522  
orange1.1g012657m A0A067EZ85 PAC:18113906 Citrus sinensis 459  
orange1.1g013618m A0A067F2S5 PAC:18113907 Citrus sinensis 439  
orange1.1g009883m A0A067FAB6 PAC:18113903 Citrus sinensis 523  
orange1.1g011156m A0A067EZ43 PAC:18113840 Citrus sinensis 492  
AT5G44070.1 Q9S7Z3 PAC:19669467 Arabidopsis thaliana 485  
AT1G03980.1 Q9ZWB7 PAC:19652275 Arabidopsis thaliana 452  
Thhalv10003194m V4LLJ7 PAC:20208031 Eutrema salsugineum 485  
Thhalv10007783m V4KYU4 PAC:20187385 Eutrema salsugineum 407  
Ciclev10019812m V4VUT6 PAC:20810113 Citrus clementina 503  
Ciclev10020222m V4TU68 PAC:20807121 Citrus clementina 433  
Ciclev10019928m V4T9P3 PAC:20809711 Citrus clementina 482  
Ciclev10019857m V4TU73 PAC:20809710 Citrus clementina 494  
Ciclev10024202m V4U4D3 PAC:20808510 Citrus clementina 494  
Lus10024921 PAC:23178879 Linum usitatissimum 631  
Lus10003623 PAC:23159179 Linum usitatissimum 195  
Lus10003622 PAC:23159163 Linum usitatissimum 514  
Potri.014G195800.1 A0A2K1XYH0 PAC:27033952 Populus trichocarpa 503  
Potri.014G195900.1 B9IBF5 PAC:27035462 Populus trichocarpa 496  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            18270423