Protein Domain : IPR019580

Type:  Domain Name:  Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding
Description:  This entry represents the interacting site for U6-snRNA, which is part of U4/U6.U5 tri-snRNPs complex of the spliceosome is a prime candidate for the role of cofactor in the spliceosome's RNA core. The essential spliceosomal protein Prp8 interacts with U5 and U6 snRNAs and with specific pre-mRNA sequences that participate in catalysis. This close association with crucial RNA sequences, together with extensive genetic evidence, suggests that Prp8 could directly affect the function of the catalytic core, perhaps acting as a splicing cofactor []. Short Name:  Prp8_U6-snRNA-bd

0 Child Features

0 Contains

1 Cross References

Identifier
PF10596

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0017070 IPR019580

1 Ontology Annotations

GO Term Gene Name
GO:0017070 IPR019580

0 Parent Features

493 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
173603 D8RRR0 PAC:15416251 Selaginella moellendorffii 2367  
evm.model.supercontig_67.49 PAC:16424731 Carica papaya 1140  
29841.m002876 B9RV85 PAC:16810589 Ricinus communis 2376  
Cucsa.105510.1 PAC:16959344 Cucumis sativus 2337  
orange1.1g042625m A0A067E0I7 PAC:18134437 Citrus sinensis 2346  
AT4G38780.1 PAC:19644973 Arabidopsis thaliana 2332  
AT1G80070.1 Q9SSD2 PAC:19650608 Arabidopsis thaliana 2359  
Thhalv10024184m V4MRX5 PAC:20195615 Eutrema salsugineum 2390  
Thhalv10017992m V4JPG7 PAC:20190986 Eutrema salsugineum 2361  
Ciclev10024683m V4RZM0 PAC:20801164 Citrus clementina 2357  
Lus10011489 PAC:23182623 Linum usitatissimum 2368  
Lus10023129 PAC:23170371 Linum usitatissimum 2370  
Potri.001G202400.1 A0A2K2C0S3 PAC:27040506 Populus trichocarpa 233  
Potri.003G031900.1 B9MWN9 PAC:26998169 Populus trichocarpa 2357  
Potri.003G031900.2 PAC:26998170 Populus trichocarpa 2067  
Gorai.009G127700.1 A0A0D2TIS8 PAC:26767783 Gossypium raimondii 2354  
Gorai.009G127700.2 A0A0D2UL43 PAC:26767784 Gossypium raimondii 2165  
Gorai.011G084400.2 A0A0D2T4K3 PAC:26810110 Gossypium raimondii 2354  
Gorai.011G084400.1 A0A0D2T4K3 PAC:26810109 Gossypium raimondii 2354  
28085 I0Z4G5 PAC:27390002 Coccomyxa subellipsoidea C-169 2308  
210656 C1N0C4 PAC:27340284 Micromonas pusilla CCMP1545 2333  
107163 C1FJT4 PAC:27399720 Micromonas sp RCC299 2336  
50795 A4S4B3 PAC:27420348 Ostreococcus lucimarinus 2320  
Thecc1EG027212t4 A0A061G8E2 PAC:27441152 Theobroma cacao 2007  
Thecc1EG027212t2 A0A061GFM4 PAC:27441150 Theobroma cacao 2354  
Thecc1EG027212t3 A0A061G7K9 PAC:27441151 Theobroma cacao 2126  
Thecc1EG027212t1 A0A061GFM4 PAC:27441149 Theobroma cacao 2354  
Migut.D01080.1.p PAC:28928633 Mimulus guttatus 2372  
Araha.2878s0002.1.p PAC:28840259 Arabidopsis halleri 2277  
Araha.16804s0021.1.p PAC:28854143 Arabidopsis halleri 2332  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            16431982