Protein Domain : IPR001985

Type:  Family Name:  S-adenosylmethionine decarboxylase
Description:  S-adenosylmethionine decarboxylase (AdoMetDC) [] catalyzes the removal of the carboxylate group of S-adenosylmethionine to form S-adenosyl-5'-3-methylpropylamine which then acts as the n-propylamine group donor in the synthesis of the polyamines spermidine and spermine from putrescine.The catalytic mechanism of AdoMetDC involves a covalently-bound pyruvoyl group. This group is post-translationally generated by a self-catalyzed intramolecular proteolytic cleavage reaction between a glutamate and a serine. This cleavage generates two chains, beta (N-terminal) and alpha (C-terminal). The N-terminal serine residue of the alpha chain is then converted by nonhydrolytic serinolysis into a pyruvyol group. Short Name:  S-AdoMet_decarboxylase
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0 Child Features

1 Contains

DB identifier Type Name
IPR018166 Conserved_site S-adenosylmethionine decarboxylase, conserved site

2 Cross Referencess

Identifier
PTHR11570
PF01536

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004014 IPR001985
GO:0006597 IPR001985
GO:0008295 IPR001985

3 Ontology Annotations

GO Term Gene Name
GO:0004014 IPR001985
GO:0006597 IPR001985
GO:0008295 IPR001985

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
100475 D8RS12 PAC:15422640 Selaginella moellendorffii 404  
106449 D8S1M3 PAC:15417816 Selaginella moellendorffii 336  
14131 D8S2S4 PAC:15408967 Selaginella moellendorffii 345  
evm.model.supercontig_16.64 PAC:16410100 Carica papaya 345  
evm.model.supercontig_53.15 PAC:16422214 Carica papaya 357  
evm.model.supercontig_70.16 PAC:16425298 Carica papaya 366  
evm.model.supercontig_718.2 PAC:16425504 Carica papaya 384  
29726.m003938 B9RSU9 PAC:16806651 Ricinus communis 342  
30138.m003848 B9RLB5 PAC:16819218 Ricinus communis 361  
27772.m000038 B9T6Z0 PAC:16799154 Ricinus communis 301  
29673.m000902 B9SIY7 PAC:16805295 Ricinus communis 359  
Cucsa.363470.1 A0A0A0KBE0 PAC:16981094 Cucumis sativus 348  
Cucsa.089960.3 PAC:16957230 Cucumis sativus 389  
Cucsa.089960.4 PAC:16957231 Cucumis sativus 389  
Cucsa.089960.1 PAC:16957228 Cucumis sativus 389  
Cucsa.089960.2 PAC:16957229 Cucumis sativus 389  
Cucsa.031490.4 PAC:16952308 Cucumis sativus 364  
Cucsa.031490.1 PAC:16952305 Cucumis sativus 364  
Cucsa.031490.2 PAC:16952306 Cucumis sativus 364  
Cucsa.031490.3 PAC:16952307 Cucumis sativus 364  
orange1.1g041801m A0A067GHK3 PAC:18106171 Citrus sinensis 343  
orange1.1g019411m PAC:18121560 Citrus sinensis 341  
orange1.1g039582m A0A067EYD7 PAC:18094166 Citrus sinensis 361  
orange1.1g035670m A0A067F857 PAC:18104173 Citrus sinensis 376  
AT5G15950.1 Q9S7T9 PAC:19666704 Arabidopsis thaliana 362  
AT5G15950.2 Q9S7T9 PAC:19666705 Arabidopsis thaliana 362  
AT5G18930.1 Q3E9D5 PAC:19667615 Arabidopsis thaliana 347  
AT3G02470.1 Q96286 PAC:19659716 Arabidopsis thaliana 366  
AT3G25570.2 Q9LSU6 PAC:19664399 Arabidopsis thaliana 349  
AT3G25570.1 Q9LSU6 PAC:19664398 Arabidopsis thaliana 349  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10378277